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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR1
All Species:
38.48
Human Site:
Y677
Identified Species:
76.97
UniProt:
P11362
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11362
NP_056934.2
822
91868
Y677
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
Chimpanzee
Pan troglodytes
XP_001171131
821
91764
Y676
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
Rhesus Macaque
Macaca mulatta
XP_001090823
731
81824
P611
T
L
G
G
S
P
Y
P
G
V
P
V
E
E
L
Dog
Lupus familis
XP_848780
820
91633
Y675
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
Cat
Felis silvestris
Mouse
Mus musculus
P16092
822
91962
Y677
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
Rat
Rattus norvegicus
Q04589
822
91806
Y677
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P21804
819
91558
Y675
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
Frog
Xenopus laevis
P22182
812
90484
Y671
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
Zebra Danio
Brachydanio rerio
Q90Z00
810
91023
Y664
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09147
1052
117795
Y918
E
S
L
Q
E
K
K
Y
D
S
Q
S
D
V
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
Y851
E
A
L
D
S
N
V
Y
T
V
E
S
D
V
W
Sea Urchin
Strong. purpuratus
Q26614
972
110463
F835
E
A
L
F
D
R
M
F
T
T
Q
S
D
V
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
85.5
98.9
N.A.
98.4
97.6
N.A.
N.A.
91.4
78.2
72.1
N.A.
30.6
N.A.
30.6
35.6
Protein Similarity:
100
99.7
86.7
99.3
N.A.
99.1
98.6
N.A.
N.A.
96.1
89.7
83.6
N.A.
45.4
N.A.
47.1
53
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
53.3
N.A.
60
80
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
73.3
N.A.
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
75
0
0
0
9
0
0
0
92
0
0
% D
% Glu:
92
0
0
0
9
0
0
0
0
0
9
0
9
9
0
% E
% Phe:
0
0
0
75
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
92
0
0
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
9
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
84
0
0
0
0
% Q
% Arg:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
17
0
0
0
0
9
0
92
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
84
9
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
17
0
9
0
92
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
92
% W
% Tyr:
0
0
0
0
0
0
9
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _